Experimental verified binding sites for PPARγ

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CYP4A6/P450 IV rabbit AACT AGGGCA A AGTTGA [1] CYP4A1/P450 IV rat AACT AGGGTA A AGTTCA [2] L-fatty acid binding protein rat ATAT AGGCCA T AGGTCA* [3] 3-hydroxy-3-methyl-glutaryl-CoA-synthase rat AACT GGGCCA A AGGTCT* [4] Enoyl-CoA-hydratase rat ATGT AGGTAA T AGTTCA* [1] Malic enzyme rat TTCT GGGTCA A AGTTGA [5] Phosphoenolpyruvate carboxikinase rat AACT GGGATA A AGGTCT [6] Phosphoenolpyruvate carboxikinase) rat CCCA CGGCCA A AGGTCA* [6] Acyl-CoA oxidase rat GACC AGGACA A AGGTCA* [1] Liver specific type 1 sugar transporter rat TTAC AGGACA A AGGCCA [7] Malic enzyme rat TTAG AGGGCA C AGGTCC* [5] Acyl-CoA oxidase rat AGCA AGGTAG A AGGTCA* [1] Acyl-CoA synthetase rat TTTC AGGGCA T CAGTCA* [8] Palmytoiltransferase fatty acid transport mouse AAGT GGGGCA A AGGGCA [9] aP2 adipocyte lipid binding protein mouse CTCT GGGTGA A ATGTGC* [10] aP2 adipocyte lipid binding protein mouse TACT GGATCA G AGTTCA [10] c-Cbl-associating protein mouse ACAC AGGCTA A AGGTCA [11] Uncoupling protein 1 mouse AGTG TGGTCA A GGGTGA* [12] Apolopoprotein C-III human GCGC TGGGCA A AGGTCA* [1] Acyl-CoA oxidase human TAGA AGGTCA G CTGTCA [13] Lipoprotein lipase human GTCT GCCCTT T CCCCCT* [14] Muscle type carnitine palmitoyltransferase I human CCTT TTCCCT A CATTTG [15] Consensus AWCT AGGNCA A AGGTCA [16] * antisense sequence reported

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تاریخ انتشار 2005